The melting temperatures of the base-pair sequences in DNA are difficult to predict. But applying statistical physics to the problem has created an 'index' that well represents the molecule's thermal properties.
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Peyrard, M. Melting the double helix. Nature Phys 2, 13–14 (2006). https://doi.org/10.1038/nphys197
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DOI: https://doi.org/10.1038/nphys197
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