Skip to main content
SpringerLink
Log in

Cancer therapy

Neutrophils traffic in cancer nanodrugs

  • News & Views
  • Published:

From Nature Nanotechnology

View current issue Submit your manuscript

Neutrophils loaded with cationic liposomal paclitaxel migrate across the blood/brain barrier to deliver chemotherapeutic nanoparticles in the inflamed post-surgical tumour margin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Schematic of the neutrophil-mediated drug-delivery system for preventing glioma recurrence after surgical resection in mice.

References

  1. Van Meir, E. G. et al. CA Cancer J. Clin. 60, 166–193 (2010).

    Article  Google Scholar 

  2. Van Meir, E. G., Sawamura, Y, Diserens, A. C., Hamou, M. F. & de Tribolet, N. Cancer Res. 50, 6683–6688 (1990).

    CAS  Google Scholar 

  3. Desbaillets, I., Diserens, A.-C., de Tribolet, N., Hamou, M.-F. & Van Meir, E. G. J. Exp. Med. 186, 1201–1212 (1997).

    Article  CAS  Google Scholar 

  4. Osuka, S. & Van Meir, E. G. J. Clin. Invest. 127, 415–426 (2017).

    Article  Google Scholar 

  5. Xue, J. et al. Nat. Nanotech. 12, 692–700 (2017).

    Article  CAS  Google Scholar 

  6. Binello, E. & Germano, I. M. Neuro. Oncol. 14, 256–265 (2012).

    Article  CAS  Google Scholar 

  7. Aboody, K. S. et al. Sci. Transl. Med. 5, 184ra59 (2013).

    Article  Google Scholar 

  8. Kolaczkowska, E. & Kubes, P. Nat. Rev. Immunol. 13, 159–175 (2013).

    Article  CAS  Google Scholar 

  9. Fossati, G. et al. Acta Neuropathol. 98, 349–354 (1999).

    Article  CAS  Google Scholar 

  10. Allen, M., Bjerke, M., Edlund, H., Nelander, S. & Westermark, B. Sci. Transl. Med. 8, 354re3 (2016).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Neurosurgery and Hematology & Medical Oncology, Satoru Osuka and Erwin G. Van Meir are in the Laboratory of Molecular Neuro-Oncology, School of Medicine and Winship Cancer Institute, Emory University, 1365C Clifton Rd. N.E., C5078, Atlanta, Georgia 30322, USA,

    Satoru Osuka & Erwin G. Van Meir

Authors
  1. Satoru Osuka
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Erwin G. Van Meir
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Satoru Osuka or Erwin G. Van Meir.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Osuka, S., Van Meir, E. Neutrophils traffic in cancer nanodrugs. Nature Nanotech 12, 616–618 (2017). https://doi.org/10.1038/nnano.2017.82

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2017.82

  • Springer Nature Limited

This article is cited by

Search

Navigation