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Redefining tumour vascular barriers

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Spontaneous formation of defects in the walls of leaky tumour blood vessels may explain the increased accumulation of large nanoparticles in certain tumours.

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Figure 1: Schematic diagram illustrating the delivery of large nanoparticles into tumours during the rare spontaneous large breaks in a blood vessel wall (dynamic vents) close to tumour cells.

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Authors and Affiliations

  1. Fitz-Roy E. Curry is in the Department of Physiology and Membrane Biology, University of California, Davis, California 95616, USA,

    Fitz-Roy E. Curry

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  1. Fitz-Roy E. Curry
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Correspondence to Fitz-Roy E. Curry.

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Curry, FR. Redefining tumour vascular barriers. Nature Nanotech 11, 494–496 (2016). https://doi.org/10.1038/nnano.2016.21

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