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Shake up the drug containers

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Lentil-shaped liposomes, formed from novel phospholipids that have an unnatural structure, release their contents only under high shear stress such as inside a constricted blood vessel, offering a way to deliver drugs to clogged arteries without the use of targeting ligands.

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Figure 1: Strategies to target drugs.

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Correspondence to Yechezkel Barenholz.

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Barenholz, Y. Shake up the drug containers. Nature Nanotech 7, 483–484 (2012). https://doi.org/10.1038/nnano.2012.132

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