Skip to main content
SpringerLink
Log in

Nanotoxicology

Nanoparticles versus the placenta

  • News & Views
  • Published:

From Nature Nanotechnology

View current issue Submit your manuscript

Pregnant mice treated 70-nm silica nanoparticles or 35-nm titanium dioxide nanoparticles suffer damage to the placenta and fetus, whereas larger nanoparticles do not have an adverse impact.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Nanoparticles (shown in red) injected into the maternal blood supply (top) must pass through three layers of trophoblast cells to enter the fetal blood.

References

  1. Saunders, M. WIREs Nanomed. Nanobiotechnol. 1, 671–684 (2009).

    Article  CAS  Google Scholar 

  2. Menezes, A., Malek, A. & Keelan, J. A. Curr. Pharm. Biotechnol. http://www.ncbi.nlm.nih.gov/pubmed/21342124 (2011).

  3. Tsuchiya, T. et al. FEBS Lett. 393, 139–145 (1996).

    Article  Google Scholar 

  4. Fujimoto, A. et al. Environ. Toxicol. 20, 431–440 (2005).

    Article  CAS  Google Scholar 

  5. Takeda, K. et al. J. Health Sci. 55, 95–102 (2009).

    Article  CAS  Google Scholar 

  6. Semmler-Behnke, M. et al. Small 4, 2108–2111 (2008).

    Article  CAS  Google Scholar 

  7. Yamashita, K. et al. Nature Nanotech. 6, 321–328 (2011).

    Article  CAS  Google Scholar 

  8. Myllynen, P. K. et al. Reprod. Toxicol. 26, 130–137 (2008).

    Article  CAS  Google Scholar 

  9. Wick, P. et al. Environ. Health Perspect. 118, 432–436 (2010).

    Article  CAS  Google Scholar 

  10. Nabeshi, H. et al. Nanoscale Res. Lett. 6, 93–98 (2011).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Jeffrey Keelan is in the School of Women's and Infants' Health, University of Western Australia at King Edward Memorial Hospital, Subiaco, Perth, Western Australia 6009, Australia,

    Jeffrey A. Keelan

Authors
  1. Jeffrey A. Keelan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jeffrey A. Keelan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Keelan, J. Nanoparticles versus the placenta. Nature Nanotech 6, 263–264 (2011). https://doi.org/10.1038/nnano.2011.65

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2011.65

  • Springer Nature Limited

This article is cited by

Search

Navigation