Two studies in this issue find that postsynaptic TRPV1 receptors affect AMPA receptor endocytosis to mediate anandamide-induced long-term depression in the hippocampus and nucleus accumbens.
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Marzo, V. Anandamide serves two masters in the brain. Nat Neurosci 13, 1446–1448 (2010). https://doi.org/10.1038/nn1210-1446
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DOI: https://doi.org/10.1038/nn1210-1446
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