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Switching gears in the spinal cord

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A study in this issue shows that zebrafish larvae deploy different groups of excitatory spinal interneurons to drive slow, fast and top speed swimming. As one set is gradually activated, the others are partially or fully inhibited.

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Figure 1: Configuration of the excitatory interneuronal network during swimming acceleration in the larval zebrafish.

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El Manira, A., Grillner, S. Switching gears in the spinal cord. Nat Neurosci 11, 1367–1368 (2008). https://doi.org/10.1038/nn1208-1367

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