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Glial progenitor cells in the adult brain reveal their alternate fate

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Glial cells that express NG2 and platelet-derived growth factor receptor α are found throughout the mature CNS. These cells are mitotically active, but their functions remain enigmatic. A genetic fate-mapping study in this issue shows that these abundant glial cells can generate both oligodendrocytes and some cortical projection neurons in the adult brain.

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Figure 1: Sites of neurogenesis in the adult brain.

Change history

  • 16 December 2008

    In the version of this article initially published, in Figure 1c, mature oligodendrocytes are incorrectly labeled as ‘NeuN+’. This should be ‘NeuN–’. The error has been corrected in the HTML and PDF versions of the article.

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Authors and Affiliations

  1. Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, WBSB 1001, Baltimore, 21205, Maryland, USA

    Shin H Kang & Dwight E Bergles

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  1. Shin H Kang
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  2. Dwight E Bergles
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Kang, S., Bergles, D. Glial progenitor cells in the adult brain reveal their alternate fate. Nat Neurosci 11, 1365–1367 (2008). https://doi.org/10.1038/nn1208-1365

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