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Sensory-motor control: a long-awaited behavioral correlate of presynaptic inhibition

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Presynaptic inhibition of cutaneous afferents influences sensory-motor responses in the spinal cord. In-vivo recordings in monkeys now show that this process suppresses the transmission of cutaneous signals generated during volitional movement.

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Figure 1: Key neurons involved in the relay of cutaneous input, via first-order interneurons in the spinal cord, to segmental motor systems and higher sensory systems.

Erin Boyle

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Authors and Affiliations

  1. Department of Physiology,

    P Ken Rose & Stephen H Scott

  2. Department of Anatomy and Cell Biology, Centre for Neuroscience Studies, Queen's University, Kingston, K7L 3N6, Ontario, Canada

    P Ken Rose & Stephen H Scott

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  1. P Ken Rose
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  2. Stephen H Scott
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Rose, P., Scott, S. Sensory-motor control: a long-awaited behavioral correlate of presynaptic inhibition. Nat Neurosci 6, 1243–1245 (2003). https://doi.org/10.1038/nn1203-1243

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