Skip to main content
SpringerLink
Log in

Long-distance signaling via presynaptic glutamate transporters

  • News & Views
  • Published:

From Nature Neuroscience

View current issue Submit your manuscript

Glutamate transporters have long been thought to help terminate the synaptic response through neurotransmitter binding and reuptake, but a new report in this issue identifies a role for their anionic current in information transmission in the retina.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Bipolar cells communicate with each other via glutamate spillover.

Lori Vaskalis

References

  1. Fairman, W.A., Vandenberg, R.J., Arriza, J.L., Kavanaugh, M.P. & Amara, S.G. Nature 375, 599–603 (1995).

    Article  CAS  Google Scholar 

  2. Wadiche, J.I., Amara, S.G. & Kavanaugh, M.P. Neuron 15, 721–728 (1995).

    Article  CAS  Google Scholar 

  3. Arriza, J.L., Eliasof, S., Kavanaugh, M.P. & Amara, S.G. Proc. Natl. Acad. Sci. USA 94, 4155–4160 (1997).

    Article  CAS  Google Scholar 

  4. Brasnjo, G. & Otis, T.S. Neuron 31, 607–616 (2001).

    Article  CAS  Google Scholar 

  5. Wadiche, J.I. & Jahr, C.E. Nat. Neurosci. 8, 1329–1334 (2005).

    Article  CAS  Google Scholar 

  6. Sarantis, M., Everett, K. & Attwell, D. Nature 332, 451–453 (1988).

    Article  CAS  Google Scholar 

  7. Picaud, S.A., Larsson, H.P., Grant, G.B., Lecar, H. & Werblin, F.S. J. Neurophysiol. 74, 1760–1771 (1995).

    Article  CAS  Google Scholar 

  8. Hasegawa, J., Obara, T., Tanaka, K. & Tachibana, M. Neuron 50, 63–74 (2006).

    Article  CAS  Google Scholar 

  9. Veruki, M.L., Morkve, S.H. & Harveit, E. Nat. Neurosci. 9, 1388–1396 (2006).

    Article  CAS  Google Scholar 

  10. Fremeau, R.T. Jr., Voglmaier, S., Seal, R.P. & Edwards, R.H. Trends Neurosci. 27, 98–103 (2004).

    Article  CAS  Google Scholar 

  11. Palmer, M.J., Taschenberger, H., Hull, C., Tremere, L. & von Gersdorff, H. J. Neurosci. 23, 4831–4841 (2003).

    Article  CAS  Google Scholar 

  12. Wersinger, E. et al. J. Physiol. (Lond.) advance online publication 14 September 2006 (doi:10.1113/jphysiol.2006.118281).

  13. Zenisek, D., Davila, V., Wan, L. & Almers, W. J. Neurosci. 23, 2538–2548 (2003).

    Article  CAS  Google Scholar 

  14. Pow, D.V. & Barnett, N.L. Cell Tissue Res. 297, 57–66 (1999).

    Article  CAS  Google Scholar 

  15. Ingram, S.L., Prasad, B.M. & Amara, S.G. Nat. Neurosci. 5, 971–978 (2002).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurobiology, University of Alabama at Birmingham, Birmingham, 35294, Alabama, USA

    Jacques I Wadiche

  2. Vollum Institute, Oregon Health and Science University, Portland, 97239, Oregon, USA

    Henrique von Gersdorff

Authors
  1. Jacques I Wadiche
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Henrique von Gersdorff
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wadiche, J., von Gersdorff, H. Long-distance signaling via presynaptic glutamate transporters. Nat Neurosci 9, 1352–1353 (2006). https://doi.org/10.1038/nn1106-1352

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn1106-1352

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation