Skip to main content
SpringerLink
Log in

Stringing the fiddle: the inner ear's two-part invention

  • News & Views
  • Published:

From Nature Neuroscience

View current issue Submit your manuscript

An Erratum to this article was published on 01 December 2007

This article has been updated

The identity of the tip link, which converts mechanical force to channel opening in hair cells, has been controversial, with different groups promoting cadherin 23 or protocadherin 15. A new paper in Nature shows that both proteins are involved.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Structure of hair bundle stereocilia and tip links.

Change history

  • 23 October 2007

    In the version of this article initially published, the legends for Figure 1d and f were switched, and citations to these panels in the text were incorrect. In addition, references to specific animal models in ref. 10 were inaccurate. The errors have been corrected in the HTML and PDF versions of the article.

References

  1. Kazmierczak, P. et al. Nature 449, 87–91 (2007).

    Article  CAS  Google Scholar 

  2. Kachar, B., Parakkal, M., Kurc, M., Zhao, Y. & Gillespie, P.G. Proc. Natl. Acad. Sci. USA 97, 13336–13341 (2000).

    Article  CAS  Google Scholar 

  3. Bork, J.M. et al. Am. J. Hum. Genet. 68, 26–37 (2001).

    Article  CAS  Google Scholar 

  4. Di Palma, F. et al. Nat. Genet. 27, 103–107 (2001).

    Article  CAS  Google Scholar 

  5. Sollner, C. et al. Nature 428, 955–959 (2004).

    Article  Google Scholar 

  6. Ahmed, Z.M. et al. Am. J. Hum. Genet. 69, 25–34 (2001).

    Article  CAS  Google Scholar 

  7. Alagramam, K.N. et al. Nat. Genet. 27, 99–102 (2001).

    Article  CAS  Google Scholar 

  8. Seiler, C. et al. Development (2005).

  9. Siemens, J. et al. Nature 428, 950–955 (2004).

    Article  CAS  Google Scholar 

  10. Michel, V. et al. Dev. Biol. 280, 281–294 (2005).

    Article  CAS  Google Scholar 

  11. Goodyear, R.J. & Richardson, G.P. J. Neurosci. 23, 4878–4887 (2003).

    Article  CAS  Google Scholar 

  12. Ahmed, Z.M. et al. J. Neurosci. 26, 7022–7034 (2006).

    Article  CAS  Google Scholar 

  13. Senften, M. et al. J. Neurosci. 26, 2060–2071 (2006).

    Article  CAS  Google Scholar 

  14. Adato, A. et al. Hum. Mol. Genet. 14, 347–356 (2005).

    Article  CAS  Google Scholar 

  15. Patel, S.D. et al. Cell 124, 1255–1268 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. David Corey is in the Howard Hughes Medical Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA. dcorey@hms.harvard.edu,

    David P Corey

Authors
  1. David P Corey
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Corey, D. Stringing the fiddle: the inner ear's two-part invention. Nat Neurosci 10, 1232–1233 (2007). https://doi.org/10.1038/nn1007-1232

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn1007-1232

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation