Skip to main content
SpringerLink
Log in

Wnts blow on NeuroD1 to promote adult neuron production and diversity

  • News & Views
  • Published:

From Nature Neuroscience

View current issue Submit your manuscript

NeuroD1 is well known for its role in development. In this issue, two papers collectively show that the Wnt pathway directly activates the transcription factor NeuroD1 to regulate adult neurogenesis and, potentially, neuron diversity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Wnts control adult neurogenesis and LINE-1 recombination.

Katie Vicari

References

  1. Zhao, C., Deng, W. & Gage, F.H. Cell 132, 645–660 (2008).

    Article  CAS  Google Scholar 

  2. Lledo, P.M., Alonso, M. & Grubb, M.S. Nat. Rev. Neurosci. 7, 179–193 (2006).

    Article  CAS  Google Scholar 

  3. Suh, H., Deng, W. & Gage, F.H. Annu. Rev. Cell Dev. Biol. published online, doi:10.1146/annurev.cellbio.042308.113256 (8 July 2009).

  4. Kriegstein, A. & Alvarez-Buylla, A. Annu. Rev. Neurosci. 32, 149–184 (2009).

    Article  CAS  Google Scholar 

  5. Ninkovic, J. & Gotz, M. Curr. Opin. Neurobiol. 17, 338–344 (2007).

    Article  CAS  Google Scholar 

  6. Kuwabara, T. et al. Nat. Neurosci. 12, 1097–1105 (2009).

    Article  CAS  Google Scholar 

  7. Gao, Z. et al. Nat. Neurosci. 12, 1090–1092 (2009).

    Article  CAS  Google Scholar 

  8. Muotri, A.R. & Gage, F.H. Nature 441, 1087–1093 (2006).

    Article  CAS  Google Scholar 

  9. Muotri, A.R. et al. Nature 435, 903–910 (2005).

    Article  CAS  Google Scholar 

  10. Lie, D.C. et al. Nature 437, 1370–1375 (2005).

    Article  CAS  Google Scholar 

  11. Bertrand, N., Castro, D.S. & Guillemot, F. Nat. Rev. Neurosci. 3, 517–530 (2002).

    Article  CAS  Google Scholar 

  12. Liu, M. et al. Proc. Natl. Acad. Sci. USA 97, 865–870 (2000).

    Article  CAS  Google Scholar 

  13. Miyata, T., Maeda, T. & Lee, J.E. Genes Dev. 13, 1647–1652 (1999).

    Article  CAS  Google Scholar 

  14. Han, J.S. & Boeke, J.D. Bioessays 27, 775–784 (2005).

    Article  CAS  Google Scholar 

  15. Hirabayashi, Y. et al. Development 131, 2791–2801 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The author is at the Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, Brussels, Belgium. pierre.vanderhaeghen@ulb.ac.be,

    Pierre Vanderhaeghen

Authors
  1. Pierre Vanderhaeghen
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vanderhaeghen, P. Wnts blow on NeuroD1 to promote adult neuron production and diversity. Nat Neurosci 12, 1079–1081 (2009). https://doi.org/10.1038/nn0909-1079

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn0909-1079

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation