A study reports a new method for wholesale labeling of neuronal proteins in situ that can visualize newly synthesized protein in a manner compatible with standard immunostaining techniques.
References
Hernandez, P.J. & Abel, T. Neurobiol. Learn. Mem. 89, 293–311 (2008).
Abraham, W.C. & Williams, J.M. Neurobiol. Learn. Mem. 89, 260–268 (2008).
Sutton, M.A. & Schuman, E.M. Cell 127, 49–58 (2006).
Dieterich, D.C. et al. Nat. Neurosci. 13, 897–905 (2010).
Link, A.J., Mock, M.L. & Tirrell, D.A. Curr. Opin. Biotechnol. 14, 603–609 (2003).
Taylor, A.M., Dieterich, D.C., Ito, H.T., Kim, S.A. & Schuman, E.M. Neuron 66, 57–68 (2010).
Ngo, J.T. et al. Nat. Chem. Biol. 5, 715–717 (2009).
Dieterich, D.C., Link, A.J., Graumann, J., Tirrell, D.A. & Schuman, E.M. Proc. Natl. Acad. Sci. USA 103, 9482–9487 (2006).
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Ariel, P., Ryan, T. Neuronal protein economics: keeping tabs on synthesis. Nat Neurosci 13, 781–782 (2010). https://doi.org/10.1038/nn0710-781
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DOI: https://doi.org/10.1038/nn0710-781
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