Cilia are increasingly appreciated regulators of brain homeostasis. Several recent studies examine the cellular and molecular mechanisms of their biogenesis and orientation in ependymal cells.
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References
Rosenbaum, J.L. & Witman, G.B. Nat. Rev. Mol. Cell Biol. 3, 813–825 (2002).
Goetz, S.C. & Anderson, K.V. Nat. Rev. Genet. 11, 331–344 (2010).
Breunig, J.J. et al. Proc. Natl. Acad. Sci. USA 105, 13127–13132 (2008).
Han, Y.G. et al. Nat. Med. 15, 1062–1065 (2009).
Han, Y.G. et al. Nat. Neurosci. 11, 277–284 (2008).
Fuchs, J.L. & Schwark, H.D. Cell Biol. Int. 28, 111–118 (2004).
Tissir, F. et al. Nat. Neurosci. 13, 700–707 (2010).
Guirao, B. et al. Nat. Cell Biol. 12, 341–350 (2010).
Mirzadeh, Z. et al. J. Neurosci. 30, 2600–2610 (2010).
Klein, T.J. & Mlodzik, M. Annu. Rev. Cell Dev. Biol. 21, 155–176 (2005).
Mirzadeh, Z. et al. Cell Stem Cell 3, 265–278 (2008).
Town, T. et al. Proc. Natl. Acad. Sci. USA 105, 2853–2858 (2008).
Banizs, B. et al. Development 132, 5329–5339 (2005).
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Breunig, J., Arellano, J. & Rakic, P. Cilia in the brain: going with the flow. Nat Neurosci 13, 654–655 (2010). https://doi.org/10.1038/nn0610-654
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DOI: https://doi.org/10.1038/nn0610-654
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