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How serotonin gates olfactory information flow

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The olfactory bulb is densely innervated by serotonergic fibers. A study now shows that serotonin activates periglomerular interneurons, which release GABA to reduce transmitter release from olfactory sensory neurons.

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Figure 1: Serotonergic control of odor inputs to the olfactory bulb.

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Authors and Affiliations

  1. Champalimaud Neuroscience Programme, Instituto Gulbenkian de Ciência, Oeiras, Portugal

    Guillaume P Dugué & Zachary F Mainen

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  1. Guillaume P Dugué
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  2. Zachary F Mainen
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Dugué, G., Mainen, Z. How serotonin gates olfactory information flow. Nat Neurosci 12, 673–675 (2009). https://doi.org/10.1038/nn0609-673

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