The transcription factor NF-κB, increasingly recognized as a key regulator of developmental and adult neural plasticity, is now reported to be essential for axon myelination as well.
This is a preview of subscription content, log in via an institution to check access.
Erin Boyle
References
Bunge, R.P., Bunge, M.B. & Bates, M. J. Cell Biol. 109, 273–284 (1989).
Nickols, J., Valentine, W., Kanwal, S. & Carter, B.D. Nat. Neurosci. 6, 161–167 (2003).
Karin, M. & Lin, A. Nat. Immunol. 3, 221–227 (2002).
Mattson, M.P. & Camandola, S. J. Clin. Invest. 107, 247–254 (2001).
Chan, J.R. et al. Proc. Natl. Acad. Sci. USA 98, 14661–14668 (2001).
Huang, C.J. et al. Int. J. Dev. Neurosci. 20, 289–296 (2002).
Stewart, H.J. et al. Glia 15, 419–436 (1995).
Fernandez-Valle et al. J. Neurobiol. 25, 1207–1226 (1994).
Nicholas, R.S., Wing, M.G. & Compston, A. Eur. J. Neurosci. 13, 959–967 (2001).
Maurel, P. & Salzer, J.L. J. Neurosci. 20, 4635–4645 (2000).
Jessen, K.R. & Mirsky, R. J. Anat. 200, 367–376 (2002).
Bartsch, U. Front. Biosci. 8, 477–490 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mattson, M. Insulating axons via NF-κB. Nat Neurosci 6, 105–106 (2003). https://doi.org/10.1038/nn0203-105
Issue Date:
DOI: https://doi.org/10.1038/nn0203-105
- Springer Nature America, Inc.
This article is cited by
-
Toll-like receptor 4-mediated nuclear factor-κB activation in spinal cord contributes to chronic morphine-induced analgesic tolerance and hyperalgesia in rats
Neuroscience Bulletin (2014)
-
Nuclear Factor κB Signaling in Opioid Functions and Receptor Gene Expression
Journal of Neuroimmune Pharmacology (2006)