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Ephrins keep dendritic spines in shape

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The EphB ephrin receptors are involved in synapse formation. New work now implicates the EphA family, as glial ephrin3A activates the EphA4 receptor on dendritic spines to stabilize spine shape.

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Figure 1: Ephrin signaling between astrocytes and neurons regulates dendritic spine shape.

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Thompson, S. Ephrins keep dendritic spines in shape. Nat Neurosci 6, 103–104 (2003). https://doi.org/10.1038/nn0203-103

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