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Recycling signaling molecules during development

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Sonic hedgehog (Shh) has many functions in development. A new study reports a key role for Shh in cell survival, proliferation and morphogenesis in formation of the forebrain and midbrain.

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Figure 1: Expansion of the neural tube requires Shh signaling.

BOB CRIMI

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Ahlgren, S., Bronner-Fraser, M. Recycling signaling molecules during development. Nat Neurosci 5, 87–88 (2002). https://doi.org/10.1038/nn0202-87

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