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Fear from the bottom up

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Two groups demonstrate the importance of inputs from the amygdala to the medial prefrontal cortex for signaling aversion across a range of behaviors and motivational drives.

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Figure 1: Amygdala inputs to the mPFC tilt behavior toward fearful responding, even in the face of competing rewards and extinction.

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Correspondence to Ekaterina Likhtik.

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Stujenske, J., Likhtik, E. Fear from the bottom up. Nat Neurosci 20, 765–767 (2017). https://doi.org/10.1038/nn.4578

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