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On being a circuit psychiatrist

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Abstract

At this unique and exciting time for psychiatry, novel therapies for individuals with mental illnesses seem just around the corner. In particular, recent technological advancements in the study of neural circuits provide reasons to be optimistic that the field is headed in the right direction. Nonetheless, maximizing the chances of translating these advancements into real improvements in patient care requires a carefully considered road map.

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References

  1. LeDoux, J. Curr. Biol. 17, R868–R874 (2007).

    Article  CAS  Google Scholar 

  2. Fanselow, M.S. & Gale, G.D. Ann. NY Acad. Sci. 985, 125–134 (2003).

    Article  Google Scholar 

  3. Davis, M. Int. Rev. Neurobiol. 36, 225–266 (1994).

    Article  CAS  Google Scholar 

  4. Morrison, S.E. & Salzman, C.D. Curr. Opin. Neurobiol. 20, 221–230 (2010).

    Article  CAS  Google Scholar 

  5. Gallagher, M. & Schoenbaum, G. Ann. NY Acad. Sci. 877, 397–411 (1999).

    Article  CAS  Google Scholar 

  6. Paton, J.J., Belova, M.A., Morrison, S.E. & Salzman, C.D. Nature 439, 865–870 (2006).

    Article  CAS  Google Scholar 

  7. Namburi, P. et al. Nature 520, 675–678 (2015).

    Article  CAS  Google Scholar 

  8. Beyeler, A. et al. Neuron 90, 348–361 (2016).

    Article  CAS  Google Scholar 

  9. Gore, F. et al. Cell 162, 134–145 (2015).

    Article  CAS  Google Scholar 

  10. Miller, G. Science 314, 1674–1676 (2006).

    Article  CAS  Google Scholar 

  11. Rakoczy, E.P. et al. Lancet 386, 2395–2403 (2015).

    Article  CAS  Google Scholar 

  12. Kelly, M.J., O'Keeffe, G.W. & Sullivan, A.M. Expert Rev. Mol. Med. 17, e8 (2015).

    Article  Google Scholar 

  13. Pleticha, J., Maus, T.P. & Beutler, A.S. Mayo Clin. Proc. 91, 522–533 (2016).

    Article  Google Scholar 

  14. Jennings, C.G. et al. Nat. Neurosci. 19, 1123–1130 (2016).

    Article  Google Scholar 

  15. Spellman, T. et al. Nature 522, 309–314 (2015).

    Article  CAS  Google Scholar 

  16. Tamura, M., Mukai, J., Gordon, J.A. & Gogos, J.A. Neuron 89, 1100–1109 (2016).

    Article  CAS  Google Scholar 

  17. Wells, M.F., Wimmer, R.D., Schmitt, L.I., Feng, G. & Halassa, M.M. Nature 532, 58–63 (2016).

    Article  CAS  Google Scholar 

  18. Lozano, A.M. & Lipsman, N. Neuron 77, 406–424 (2013).

    Article  CAS  Google Scholar 

  19. Chervyakov, A.V., Chernyavsky, A.Y., Sinitsyn, D.O. & Piradov, M.A. Front. Hum. Neurosci. 9, 303 (2015).

    Article  Google Scholar 

  20. Sullivan, P.F., Daly, M.J. & O'Donovan, M. Nat. Rev. Genet. 13, 537–551 (2012).

    Article  CAS  Google Scholar 

  21. Estes, M.L. & McAllister, A.K. Science 353, 772–777 (2016).

    Article  CAS  Google Scholar 

  22. Nemeroff, C.B. Neuron 89, 892–909 (2016).

    Article  CAS  Google Scholar 

  23. Heckenast, J.R., Wilkinson, L.S. & Jones, M.W. Adv. Genet. 92, 75–106 (2015).

    Article  CAS  Google Scholar 

  24. Glasser, M.F. et al. Nat. Neurosci. 19, 1175–1187 (2016).

    Article  Google Scholar 

Download references

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Correspondence to Joshua A Gordon.

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Gordon, J. On being a circuit psychiatrist. Nat Neurosci 19, 1385–1386 (2016). https://doi.org/10.1038/nn.4419

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