Skip to main content
SpringerLink
Log in

Crash course in pallidus–habenula signaling

  • News & Views
  • Published:

From Nature Neuroscience

View current issue Submit your manuscript

During cocaine withdrawal, a shift in the balance between excitatory and inhibitory inputs from globus pallidus to lateral habenula may activate habenula and contribute to the aversive 'crash' state.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Shift in balance between inhibitory and excitatory input from pallidum to habenula during cocaine withdrawal.

References

  1. Jhou, T.C. et al. J. Neurosci. 33, 7501–7512 (2013).

    Article  CAS  Google Scholar 

  2. Meye, F.J. et al. Nat. Neurosci. 18, 376–378 (2015).

    Article  CAS  Google Scholar 

  3. Matsumoto, M. & Hikosaka, O. Nature 447, 1111–1115 (2007).

    Article  CAS  Google Scholar 

  4. Sartorius, A. & Henn, F.A. Med. Hypotheses 69, 1305–1308 (2007).

    Article  Google Scholar 

  5. Jhou, T.C., Fields, H.L., Baxter, M.G., Saper, C.B. & Holland, P.C. Neuron 61, 786–800 (2009).

    Article  CAS  Google Scholar 

  6. Gonçalves, L., Sego, C. & Metzger, M. J. Comp. Neurol. 520, 1278–1300 (2012).

    Article  Google Scholar 

  7. Maroteaux, M. & Mameli, M. J. Neurosci. 32, 12641–12646 (2012).

    Article  CAS  Google Scholar 

  8. Bromberg-Martin, E.S., Matsumoto, M., Hong, S. & Hikosaka, O. J. Neurophysiol. 104, 1068–1076 (2010).

    Article  Google Scholar 

  9. Proulx, C.D., Hikosaka, O. & Malinow, R. Nat. Neurosci. 17, 1146–1152 (2014).

    Article  CAS  Google Scholar 

  10. Shabel, S.J., Proulx, C.D., Piriz, J. & Malinow, R. Science 345, 1494–1498 (2014).

    Article  CAS  Google Scholar 

  11. Hong, S. & Hikosaka, O. Neuron 60, 720–729 (2008).

    Article  CAS  Google Scholar 

  12. Wickersham, I.R. et al. Neuron 53, 639–647 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Masago Ishikawa and Paul J. Kenny are in the Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.,

    Masago Ishikawa & Paul J Kenny

Authors
  1. Masago Ishikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Paul J Kenny
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Paul J Kenny.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ishikawa, M., Kenny, P. Crash course in pallidus–habenula signaling. Nat Neurosci 19, 981–983 (2016). https://doi.org/10.1038/nn.4349

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn.4349

  • Springer Nature America, Inc.

Search

Navigation