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Back to the past in schizophrenia genomics

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Conclusive evidence for defective neurodevelopment in schizophrenia is lacking. Two DNA methylation studies now draw a link between fetal brain epigenomes, epigenetic alterations in the adult diseased brain and genetic risk for the disease.

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Figure 1: DNA methylation signatures in schizophrenia brain connect past and present.

Katie Vicari/Nature Publishing Group

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Correspondence to Andrew J Sharp or Schahram Akbarian.

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Sharp, A., Akbarian, S. Back to the past in schizophrenia genomics. Nat Neurosci 19, 1–2 (2016). https://doi.org/10.1038/nn.4203

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