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Thalamus controls recurrent cortical dynamics

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Previous work has suggested that cortical recurrent circuits can self-sustain their activity without thalamic input. A study now demonstrates that this is not the case in the awake brain, which tightly locks cortical timing to thalamic activity.

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Figure 1: The influence of thalamic inputs in visual cortical responses.

References

  1. Reinhold, K., Lien, T. & Scanziani, M. Nat. Neurosci. 18, 1789–1797 (2015).

    Article  CAS  Google Scholar 

  2. Ferster, D., Chung, S. & Wheat, H. Nature 380, 249–252 (1996).

    Article  CAS  Google Scholar 

  3. Li, Y.T., Ibrahim, L.A., Liu, B.H., Zhang, L.I. & Tao, H.W. Nat. Neurosci. 16, 1324–1330 (2013).

    Article  CAS  Google Scholar 

  4. Lien, A.D. & Scanziani, M. Nat. Neurosci. 16, 1315–1323 (2013).

    Article  CAS  Google Scholar 

  5. Sanchez-Vives, M.V. & McCormick, D.A. Nat. Neurosci. 3, 1027–1034 (2000).

    Article  CAS  Google Scholar 

  6. Timofeev, I., Grenier, F., Bazhenov, M., Sejnowski, T.J. & Steriade, M. Cereb. Cortex 10, 1185–1199 (2000).

    Article  CAS  Google Scholar 

  7. Constantinople, C.M. & Bruno, R.M. Neuron 69, 1061–1068 (2011).

    Article  CAS  Google Scholar 

  8. Gil, Z., Connors, B.W. & Amitai, Y. Neuron 19, 679–686 (1997).

    Article  CAS  Google Scholar 

  9. Castro-Alamancos, M.A. & Oldford, E. J. Physiol. (Lond.) 541, 319–331 (2002).

    Article  CAS  Google Scholar 

  10. Swadlow, H.A. & Gusev, A.G. Nat. Neurosci. 4, 402–408 (2001).

    Article  CAS  Google Scholar 

  11. Bezdudnaya, T. et al. Neuron 49, 421–432 (2006).

    Article  CAS  Google Scholar 

  12. Sherman, S.M. & Guillery, R.W. Exploring the Thalamus (Academic Press, New York, 2000).

    Google Scholar 

  13. Stoelzel, C.R., Bereshpolova, Y., Gusev, A.G. & Swadlow, H.A. J. Neurosci. 28, 5018–5028 (2008).

    Article  CAS  Google Scholar 

  14. Martinez, L.M. & Alonso, J.M. Neuron 32, 515–525 (2001).

    Article  CAS  Google Scholar 

  15. Malpeli, J.G. J. Neurophysiol. 49, 595–610 (1983).

    Article  CAS  Google Scholar 

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Correspondence to Jose Manuel Alonso or Harvey A Swadlow.

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Alonso, J., Swadlow, H. Thalamus controls recurrent cortical dynamics. Nat Neurosci 18, 1703–1704 (2015). https://doi.org/10.1038/nn.4175

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