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Promoting FOS to an enhanced position

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How do enhancers facilitate transcription of plasticity-related genes in response to synaptic stimulation? A study implicates a specific histone modification and suggests that FOS regulates enhancer function.

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Figure 1: Identifying active neuronal enhancers.

Debbie Maizels/Nature Publishing Group

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Authors and Affiliations

  1. Sietse Jonkman and Paul J. Kenny are in the Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York, USA.,

    Sietse Jonkman & Paul J Kenny

Authors
  1. Sietse Jonkman
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  2. Paul J Kenny
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Correspondence to Paul J Kenny.

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The authors declare no competing financial interests.

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Jonkman, S., Kenny, P. Promoting FOS to an enhanced position. Nat Neurosci 17, 1291–1293 (2014). https://doi.org/10.1038/nn.3819

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