In synaptic integration, timing is everything. A new study demonstrates that voltage-activated ion channels transform spatially distributed synaptic input into a coherent neuronal output by countering time delays in the dendritic tree.
Access this article
We’re sorry, something doesn't seem to be working properly.
Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.
References
Vaidya, S.P. & Johnston, D. Nat. Neurosci. 16, 1812–1820 (2013).
Rall, W. in Neuronal Theory and Modeling (ed. Reiss, R.F.) 73–97 (Stanford Univ. Press, 1964).
Robinson, R.B. & Siegelbaum, S.A. Annu. Rev. Physiol. 65, 453–480 (2003).
Narayanan, R. & Johnston, D. J. Neurosci. 28, 5846–5860 (2008).
Magee, J.C. J. Neurosci. 18, 7613–7624 (1998).
Lörincz, A., Notomi, T., Tamas, G., Shigemoto, R. & Nusser, Z. Nat. Neurosci. 5, 1185–1193 (2002).
Buzsáki, G. Rhythms of the Brain (Oxford University Press, USA, 2011).
Hu, H., Vervaeke, K., Graham, L.J. & Storm, J.F. J. Neurosci. 29, 14472–14483 (2009).
Magee, J.C. Nat. Neurosci. 2, 508–514 (1999).
Kleindienst, T., Winnubst, J., Roth-Alpermann, C., Bonhoeffer, T. & Lohmann, C. Neuron 72, 1012–1024 (2011).
Losonczy, A., Makara, J.K. & Magee, J.C. Nature 452, 436–441 (2008).
Magee, J.C. & Cook, E.P. Nat. Neurosci. 3, 895–903 (2000).
Nicholson, D.A. et al. Neuron 50, 431–442 (2006).
Fan, Y. et al. Nat. Neurosci. 8, 1542–1551 (2005).
Campanac, E., Daoudal, G., Ankri, N. & Debanne, D. J. Neurosci. 28, 8635–8643 (2008).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Williams, S. Synchrony and the single neuron. Nat Neurosci 16, 1714–1715 (2013). https://doi.org/10.1038/nn.3586
Published:
Issue Date:
DOI: https://doi.org/10.1038/nn.3586
- Springer Nature America, Inc.