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Brain microglia: watchdogs with pedigree

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Microglia have been regarded as the tissue macrophages of the brain. A study now finds that microglia are quite distinct from blood-borne macrophages and derive from an erythromyeloid precursor cell of the embryonic hematopoiesis.

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Figure 1: Pedigrees of microglial and macrophage lineages.

Katie Vicari

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Authors and Affiliations

  1. Harald Neumann is at the Institute of Reconstructive Neurobiology, University Bonn, Bonn, Germany,

    Harald Neumann

  2. Hartmut Wekerle is at the Max Planck Institute of Neurobiology, Martinsried, Germany.,

    Hartmut Wekerle

Authors
  1. Harald Neumann
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  2. Hartmut Wekerle
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Correspondence to Hartmut Wekerle.

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The authors declare no competing financial interests.

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Neumann, H., Wekerle, H. Brain microglia: watchdogs with pedigree. Nat Neurosci 16, 253–255 (2013). https://doi.org/10.1038/nn.3338

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