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Fragile balance: RNA editing tunes the synapse

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Orchestration of gene expression enables coordination between the nucleus and synapses. A report now uncovers a function for the fragile X mental retardation protein in RNA editing necessary for synaptic development.

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Figure 1: Regulation of A-to-I RNA editing by FMRP in Drosophila.

Katie Vicari

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Correspondence to Gary J Bassell.

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Bassell, G. Fragile balance: RNA editing tunes the synapse. Nat Neurosci 14, 1492–1494 (2011). https://doi.org/10.1038/nn.2982

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