CB2 receptors, expressed mainly by immune cells in the periphery, are thought to be minimally involved in cannabinoid signaling in brain. However, a study now finds that brain CB2 receptors may be central to cocaine addiction.
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Kenny, P. 'Macrophage' cannabinoid receptor goes up in smoke. Nat Neurosci 14, 1100–1102 (2011). https://doi.org/10.1038/nn.2912
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DOI: https://doi.org/10.1038/nn.2912
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