Technological breakthroughs in cryo-electron microscopy are allowing the capture of virus structures, leading to advances in the field of viral microbiology almost daily. An innovative structure–function study on Aichi virus reveals that novel entry mechanisms, yet undiscovered, may exist for non-enveloped viruses.
References
Fendrick, A. M., Monto, A. S., Nightengale, B. & Sarnes, M. Arch. Intern. Med. 163, 487–494 (2003).
Zhu, L. et al. Nat. Microbiol. 1, 16150 (2016).
Rossmann, M. G. et al. Nature 317, 145–153 (1985).
Hogle, J. M., Chow, M. & Filman, D. J. Science 27, 1358–1365 (1985).
Zhu, L. et al. Nat. Commun. 6, 8316 (2015).
Wang, X. et al. Nature 517, 85–88 (2015).
Ren, J. et al. J. Virol. 89, 10500–10511 (2015).
Shakeel, S. et al. J. Virol. 89, 9571–9580 (2015).
Ren, J. et al. Nat. Commun. 4, 1929 (2013).
Pickl-Herk, A. et al. Proc. Natl Acad. Sci. USA 110, 20063–20068 (2013).
Strauss, M. et al. J. Virol. 89, 4143–4157 (2015).
Lee, H. et al. Sci. Adv. 2, e1501929 (2016).
Kotecha, A. et al. Nat. Struct. Mol. Biol. 22, 788–794 (2015).
Chebrek, R., Leonard, S., de Brevern, A. G. & Gelly, J.-C. Database (Oxford) 2014, bau102 (2014).
Adzhubei, A. A., Sternberg, M. J. & Makarov, A. A. J. Mol. Biol. 425, 2100–2132 (2013).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hafenstein, S. Structural biology: A picornavirus unlike the others. Nat Microbiol 1, 16217 (2016). https://doi.org/10.1038/nmicrobiol.2016.217
Published:
DOI: https://doi.org/10.1038/nmicrobiol.2016.217
- Springer Nature Limited