Skip to main content
Log in

Pacing lightly: optogenetics gets to the heart

  • News & Views
  • Published:

From Nature Methods

View current issue Submit your manuscript

Transfer of the light-activated cation channel channelrhodopsin-2 gene enables optical control of heart muscle membrane potential.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Optogenetic control of heart muscle.

References

  1. Bruegmann, T. et al. Nat. Methods 7, 897–900 (2010).

    Article  CAS  Google Scholar 

  2. Gurney, A.M., Charnet, P., Pye, J.M. & Nargeot, J. Nature 341, 65–68 (1989).

    Article  CAS  Google Scholar 

  3. Jenkins, M.W. et al. Nat. Photonics 4, 623–626 (2010).

    Article  CAS  Google Scholar 

  4. Boyden, E.S., Zhang, F., Bamberg, E., Nagel, G. & Deisseroth, K. Nat. Neurosci. 8, 1263–1268 (2005).

    Article  CAS  Google Scholar 

  5. Chang, M.G. et al. Circ. Res. 105, 1062–1071 (2009).

    Article  CAS  Google Scholar 

  6. Xie, Y., Sato, D., Garfinkel, A., Qu, Z. & Weiss, J.N. Biophys. J. 99, 1408–1415 (2010).

    Article  CAS  Google Scholar 

  7. Adeyemi, A.A., Barakat, N. & Darcie, T.E. Opt. Express 17, 1831–1843 (2009).

    Article  Google Scholar 

  8. Roell, W. et al. Nature 450, 819–824 (2007).

    Article  CAS  Google Scholar 

  9. Zhang, F. et al. Nature 446, 633–639 (2007).

    Article  CAS  Google Scholar 

  10. Chow, B.Y. et al. Nature 463, 98–102 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Björn C Knollmann.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Knollmann, B. Pacing lightly: optogenetics gets to the heart. Nat Methods 7, 889–891 (2010). https://doi.org/10.1038/nmeth1110-889

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth1110-889

  • Springer Nature America, Inc.

This article is cited by

Navigation