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Adding a spatial dimension to the proteome

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Abstract

A 'visual proteomics' approach combining quantitative mass spectrometry and cryo-electron tomography offers a window into the spatial arrangement of protein complexes in the human pathogen Leptospira interrogans.

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Figure 1: Integration of quantitative proteomics and cryo-electron tomography data.

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Authors and Affiliations

  1. Kay Grünewald is at the Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, Oxford, UK.,

    Kay Grünewald

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  1. Kay Grünewald
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Correspondence to Kay Grünewald.

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Grünewald, K. Adding a spatial dimension to the proteome. Nat Methods 6, 798–800 (2009). https://doi.org/10.1038/nmeth1109-798

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