A portable fiber-optic epifluorescence microscope allows real-time imaging of brain function with cellular spatial resolution in freely moving mice.
References
Flusberg, B.A. et al. Nat. Methods 5, 935–938 (2008).
Helmchen, F. & Denk, W. Nat. Methods 2, 932–940 (2005).
Dombeck, D.A., Khabbaz, A.N., Collman, F., Adelman, T.L. & Tank, D.W. Neuron 56, 43–57 (2007).
Helmchen, F., Fee, M.S., Tank, D.W. & Denk, W. Neuron 31, 903–912 (2001).
Flusberg, B.A. et al. Nat. Methods 2, 941–950 (2005).
Ferezou, I., Bolea, S. & Petersen, C.C.H. Neuron 50, 617–629 (2006).
Dirnagl, U., Villringer, A. & Einhaupl, K.M. J. Microsc. 165, 147–157 (1992).
Sullivan, M.R., Nimmerjahn, A., Sarkisov, D.V., Helmchen, F. & Wang, S.S. J. Neurophysiol. 94, 1636–1644 (2005).
Ozden, I., Lee, H.M., Sullivan, M.R. & Wang, S.S. J. Neurophysiol. 100, 495–503 (2008).
Engelbrecht, C.J., Johnston, R.S., Seibel, E.J. & Helmchen, F. Opt. Express 16, 5556–5564 (2008).
Flusberg, B.A., Jung, J.C., Cocker, E.D., Anderson, E.P. & Schnitzer, M.J. Opt. Lett. 30, 2272–2274 (2005).
Adelsberger, H., Garaschuk, O. & Konnerth, A. Nat. Neurosci. 8, 988–990 (2005).
Murayama, M., Pérez-Garci, E., Lüscher, H.R. & Larkum, M.E. J. Neurophysiol. 98, 1791-1805 (2007).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Helmchen, F., Petersen, C. New views into the brain of mice on the move. Nat Methods 5, 925–926 (2008). https://doi.org/10.1038/nmeth1108-925
Issue Date:
DOI: https://doi.org/10.1038/nmeth1108-925
- Springer Nature America, Inc.
This article is cited by
-
Optical brush: Imaging through permuted probes
Scientific Reports (2016)