Abstract
An uncharged CoA precursor that can enter the cell is used for covalent, site-specific labeling of proteins inside living cells.
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References
Clarke, K.M., et al. In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues. J. Am. Chem. Soc. 127, 11234–11235 (2005).
Meier, J.L. et al. Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification. J. Am. Chem. Soc. 128, 12174–12184 (2006).
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Kaganman, I. The inside tag. Nat Methods 3, 872–873 (2006). https://doi.org/10.1038/nmeth1106-872b
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DOI: https://doi.org/10.1038/nmeth1106-872b
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