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The External RNA Controls Consortium: a progress report

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Standard controls and best practice guidelines advance acceptance of data from research, preclinical and clinical laboratories by providing a means for evaluating data quality. The External RNA Controls Consortium (ERCC) is developing commonly agreed-upon and tested controls for use in expression assays, a true industry-wide standard control.

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Figure 1: The expression assay process.

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Author information

Authors and Affiliations

  1. Illumina, Inc., 9885 Towne Centre Drive, San Diego, 92121, California, USA

    Shawn C Baker

  2. US Food and Drug Administration, Center for Biologics Evaluation and Research, Building 29B/2NN12, HFM-521, 1401 Rockville Pike, Rockville, 20852, Maryland, USA

    Steven R Bauer

  3. University of Washington, 4225 Roosevelt Way NE, Seattle, 98105, Washington, USA

    Richard P Beyer & Kathleen Kerr

  4. Cambridge University, Cambridge Institute for Medical Research (CIMR), Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2XY, UK

    James D Brenton

  5. ViaLogy Corporation, 2400 Lincoln Avenue, Altadena, 91001, California, USA

    Bud Bromley

  6. Applied Biosystems, 850 Lincoln Center Drive, Foster City, 94404, California, USA

    John Burrill, Raymond R Samaha & Timothy J Sendera

  7. University of London, Imperial College of London, London, SW7 2AZ, UK

    Helen Causton

  8. Enzo Life Sciences, Inc., 60 Executive Boulevard, Farmingdale, 11735, New York, USA

    Michael P Conley

  9. US Food and Drug Administration, Center for Devices and Radiological Health, Federal Laboratories at White Oak, Life Sciences Building 64, Room 3020, 10903 New Hampshire Avenue, Silver Spring, 20903, Maryland, USA

    Rosalie Elespuru

  10. Stanford University School of Medicine, CCSR 4256, 269 Campus Drive, Stanford, 94305, California, USA

    Michael Fero

  11. LGC, Bio-Molecular Innovation, Queens Road, Teddington, TW11OLY, UK

    Carole Foy & Helen Parkes

  12. US Food and Drug Administration, National Center for Toxicological Research, 3900 NCTR Road, HFT-020, Jefferson, 72079, Arkansas, USA

    James Fuscoe & Leming Shi

  13. Atactic Technology, Inc., 2575 W. Bellfort, Suite 270, Houston, 77054, Texas, USA

    Xiaolian Gao

  14. Department of Molecular Profiling, Merck Research Laboratories, West Point, 19486, Pennsylvania, USA

    David Lee Gerhold

  15. Invitrogen Corporation, 1600 Faraday Avenue, P.O. Box 6482, Carlsbad, 92008, California, USA

    Patrick Gilles

  16. US Food and Drug Administration, Center for Drug Evaluation and Research, 1451 Rockville Pike (HFD-860), Woodmont II Office 2078, Rockville, 20852, Maryland, USA

    Federico Goodsaid

  17. Affymetrix Inc., 3380 Central Expressway, Santa Clara, 95051, California, USA

    Xu Guo, Chunmei Liu, Garry Miyada, Thomas B Ryder & Janet A Warrington

  18. US Food and Drug Administration, Center for Devices and Radiological Health, HFZ-440, 2098 Oak Grove, Rockville, 20850, Maryland, USA

    Joe Hackett

  19. Eli Lilly and Company, Lilly Research Lab, Lilly Corporate Center, Indianapolis, 46285, Indiana, USA

    Richard D Hockett

  20. American Type Culture Collection, 10801 University Boulevard, Manassas, 20110, Virginia, USA

    Pranvera Ikonomi

  21. Johns Hopkins School of Public Health, 615 N. Wolfe St. E3132, Baltimore, 21205, Maryland, USA

    Rafael A Irizarry

  22. National Cancer Institute Advanced Technology Center, National Institutes of Health, 8717 Grovemont Circle, Bethesda, 20892, Maryland, USA

    Ernest S Kawasaki

  23. GE Healthcare, 3200 W. Germann Road, Chandler, 85248, Arizona, USA

    Tamma Kaysser-Kranich, Gretchen Kiser & Richard Shippy

  24. Roche Molecular Systems, 4300 Hacienda Dr., Pleasanton, 94588, California, USA

    Walter H Koch, Kathy Y Lee, Mickey Williams & Xiaoning Wu

  25. US Department of Ariculture, 1815 N. University Street, Peoria, 61604, Illinois, USA

    Z Lewis Liu

  26. Agilent Technologies, Inc., 5301 Stevens Creek Blvd. MS 55L WM, Santa Clara, 95051, California, USA

    Anne Lucas & Paul K Wolber

  27. Lawrence Livermore National Laboratory Microarray Center, 7000 East Avenue, Livermore, 94550, California, USA

    Chitra F Manohar

  28. Genentech, 1 DNA Way, South San Francisco, 94080, California, USA

    Zora Modrusan

  29. US Food and Drug Administration, NIH Building 29B, Room 2NN10, 29 Lincoln Drive MSC 4555, Bethesda, 20892, Maryland, USA

    Raj K Puri

  30. Expression Analysis, 2605 Meridian Parkway, Durham, 27713, North Carolina, USA

    Laura Reid

  31. National Institute of Standards and Technology, Chemical Science and Technology Laboratory, 100 Bureau Drive, Stop 8391, Gaithersburg, 20899, Maryland, USA

    Marc Salit

  32. US Food and Drug Administration, Office of In Vitro Diagnostic Device Evaluation and Safety, OAK8, RM366, HFZ-440, 2098 Gaither Road, Rockville, 20850, Maryland, USA

    Uwe Scherf

  33. Ambion, Inc., 2130 Woodward St., Austin, 78744, Texas, USA

    Robert A Setterquist & Mike Wilson

  34. American Type Culture Collection, 10801 University Boulevard, Manassas, 20110, Virgnia, USA

    Jesus V Soriano

  35. UCLA Clinical Laboratories, 10833 Le Conte Avenue, Los Angeles, 90095, California, USA

    Elizabeth A Wagar

  36. Qiagen Inc., Hilden, 40727, Germany

    Frederike Wilmer

  37. Zagreb University School of Medicine, Medical School, Zagreb, 10 000 3, Salata, Croatia

    Renata Zadro

Consortia

The External RNA Controls Consortium

  • Shawn C Baker
  • , Steven R Bauer
  • , Richard P Beyer
  • , James D Brenton
  • , Bud Bromley
  • , John Burrill
  • , Helen Causton
  • , Michael P Conley
  • , Rosalie Elespuru
  • , Michael Fero
  • , Carole Foy
  • , James Fuscoe
  • , Xiaolian Gao
  • , David Lee Gerhold
  • , Patrick Gilles
  • , Federico Goodsaid
  • , Xu Guo
  • , Joe Hackett
  • , Richard D Hockett
  • , Pranvera Ikonomi
  • , Rafael A Irizarry
  • , Ernest S Kawasaki
  • , Tamma Kaysser-Kranich
  • , Kathleen Kerr
  • , Gretchen Kiser
  • , Walter H Koch
  • , Kathy Y Lee
  • , Chunmei Liu
  • , Z Lewis Liu
  • , Anne Lucas
  • , Chitra F Manohar
  • , Garry Miyada
  • , Zora Modrusan
  • , Helen Parkes
  • , Raj K Puri
  • , Laura Reid
  • , Thomas B Ryder
  • , Marc Salit
  • , Raymond R Samaha
  • , Uwe Scherf
  • , Timothy J Sendera
  • , Robert A Setterquist
  • , Leming Shi
  • , Richard Shippy
  • , Jesus V Soriano
  • , Elizabeth A Wagar
  • , Janet A Warrington
  • , Mickey Williams
  • , Frederike Wilmer
  • , Mike Wilson
  • , Paul K Wolber
  • , Xiaoning Wu
  •  & Renata Zadro

Corresponding author

Correspondence to Janet A Warrington.

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The External RNA Controls Consortium. The External RNA Controls Consortium: a progress report. Nat Methods 2, 731–734 (2005). https://doi.org/10.1038/nmeth1005-731

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  • DOI: https://doi.org/10.1038/nmeth1005-731

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