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Hold me tightly LOV

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Mutations that increase the dynamic range of a photoswitchable protein may be used to improve other such photoswitches and increase their potential for allosteric control of protein activity in live cells.

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Figure 1: LOV domain–based photoswitches.

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Authors and Affiliations

  1. Klaus M. Hahn and Brian Kuhlman are at the University of North Carolina, Chapel Hill, North Carolina, USA.,

    Klaus M Hahn & Brian Kuhlman

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  1. Klaus M Hahn
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  2. Brian Kuhlman
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Correspondence to Klaus M Hahn or Brian Kuhlman.

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Hahn, K., Kuhlman, B. Hold me tightly LOV. Nat Methods 7, 595–596 (2010). https://doi.org/10.1038/nmeth0810-595

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