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The charged sialic acid exhibits its power again: a new high-throughput screening technology

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In this issue, the Withers laboratory takes advantage of the negatively charged sialic acid to develop a high-throughput screening technology that can be used for evolving glycosyltransferases with new enzymatic activities.

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Figure 1: High-thoughput screening methodology for evolving sialyltransferases.

Simon Fenwick

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Wang, P. The charged sialic acid exhibits its power again: a new high-throughput screening technology. Nat Methods 3, 589–590 (2006). https://doi.org/10.1038/nmeth0806-589

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