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Mining for natural products

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Abstract

Using phage display and a biotin-based selection system, researchers clone genes involved in natural product biosynthesis in bacteria.

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Figure 1: High-throughput cloning of bacterial carrier proteins.

References

  1. Yin, J. et al. Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display. Chem. Biol. 14, 303–312 (2007).

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Authors
  1. Natalie de Souza
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de Souza, N. Mining for natural products. Nat Methods 4, 470–471 (2007). https://doi.org/10.1038/nmeth0607-470a

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  • DOI: https://doi.org/10.1038/nmeth0607-470a

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