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Efficient maximum likelihood estimator fitting of histograms

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Figure 1: Fluorescence lifetime imaging data for Y. pestis constitutively expressing EGFP.

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Acknowledgements

This work was performed under the auspices of the US Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344.

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Authors and Affiliations

  1. Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California, USA

    Ted A Laurence & Brett A Chromy

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  1. Ted A Laurence
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  2. Brett A Chromy
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Correspondence to Ted A Laurence.

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The authors declare no competing financial interests.

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Supplementary Text and Figures

Supplementary Note (PDF 870 kb)

Supplementary Software

C code for Levenberg-Marquardt minimization of MLE. (ZIP 17 kb)

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Laurence, T., Chromy, B. Efficient maximum likelihood estimator fitting of histograms. Nat Methods 7, 338–339 (2010). https://doi.org/10.1038/nmeth0510-338

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