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Large-scale genetic epistasis networks using RNAi

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Abstract

Pairwise quantitative genetic interactions are mapped by combinatorial RNA interference in metazoan cells.

Pairwise quantitative genetic interactions are mapped by combinatorial RNA interference in metazoan cells.

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Figure 1: Workflow of a combinatorial RNAi screen for genetic interactions developed by Horn et al.2.

References

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Authors and Affiliations

  1. Xiaoyue Wang and Kevin P. White are at the Institute for Genomics and Systems Biology and Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.,

    Xiaoyue Wang & Kevin P White

Authors
  1. Xiaoyue Wang
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  2. Kevin P White
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Corresponding author

Correspondence to Kevin P White.

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The authors declare no competing financial interests.

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Wang, X., White, K. Large-scale genetic epistasis networks using RNAi. Nat Methods 8, 299–301 (2011). https://doi.org/10.1038/nmeth0411-299

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