Skip to main content
Log in

Tracking microscopy enables whole-brain imaging in freely moving zebrafish

  • News & Views
  • Published:

From Nature Methods

View current issue Submit your manuscript

Efficient tracking and optical whole-brain imaging at single-cell resolution in freely behaving zebrafish larvae pave the way for quantitative investigation of circuits underlying complex behaviors.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Imaging whole-brain neuronal activity at single-cell resolution is now possible in freely moving zebrafish larvae performing complex sensory–motor tasks.

Kim Caesar/Springer Nature

References

  1. Symvoulidis, P. et al. Nat. Methods 14, 1079–1082 (2017).

    Article  CAS  Google Scholar 

  2. Kim, D.H. et al. Nat. Methods 14, 1107–1114 (2017).

    Article  CAS  Google Scholar 

  3. Cong, L. et al. eLife http://dx.doi.org/10.7554/eLife.28158 (2017).

  4. Nguyen, J.P. et al. Proc. Natl. Acad. Sci. USA 113, E1074–E1081 (2016).

    Article  CAS  Google Scholar 

  5. Ahrens, M.B., Orger, M.B., Robson, D.N., Li, J.M. & Keller, P.J. Nat. Methods 10, 413–420 (2013).

    Article  CAS  Google Scholar 

  6. Wolf, S. et al. Nat. Methods 12, 379–380 (2015).

    Article  CAS  Google Scholar 

  7. Knafo, S. et al. eLife 6, e25260 (2017).

    Article  Google Scholar 

  8. Lim, D., Ford, T.N., Chu, K.K. & Mertz, J. J. Biomed. Opt. 16, 016014 (2011).

    Article  Google Scholar 

  9. Broxton, M. et al. Opt. Express 21, 25418–25439 (2013).

    Article  Google Scholar 

  10. Prevedel, R. et al. Nat. Methods 11, 727–730 (2014).

    Article  CAS  Google Scholar 

  11. Horstmeyer, R., Ruan, H. & Yang, C. Nat. Photonics 9, 563–571 (2015).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Claire Wyart.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Thouvenin, O., Wyart, C. Tracking microscopy enables whole-brain imaging in freely moving zebrafish. Nat Methods 14, 1041–1042 (2017). https://doi.org/10.1038/nmeth.4474

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.4474

  • Springer Nature America, Inc.

This article is cited by

Navigation