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Chemistry

A fix for formaldehyde fixation

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Researchers use chemistry to solve a nagging problem that has challenged the analysis of RNA from formaldehyde-fixed tissue specimens.

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References

  1. Karmakar, S. et al. Organocatalytic removal of formaldehyde adducts from RNA and DNA bases. Nat. Chem. 7, 752–758 (2015).

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Authors
  1. Allison Doerr
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Doerr, A. A fix for formaldehyde fixation. Nat Methods 12, 906–907 (2015). https://doi.org/10.1038/nmeth.3607

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  • DOI: https://doi.org/10.1038/nmeth.3607

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