Skip to main content
Log in

Comprehensive macromolecular conformations mapped by quantitative SAXS analyses

  • Correspondence
  • Published:

From Nature Methods

View current issue Submit your manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: SAXS applied to measure structural similarity.

References

  1. Hura, G.L. et al. Nat. Methods 6, 606–612 (2009).

    Article  CAS  Google Scholar 

  2. Moore, P.B. J. Appl. Crystallogr. 13, 168–175 (1980).

    Article  CAS  Google Scholar 

  3. Yang, Y., Faraggi, E., Zhao, H. & Zhou, Y. Bioinformatics 27, 2076–2082 (2011).

    Article  CAS  Google Scholar 

  4. Svergun, D., Barberato, C. & Koch, M.H.J. J. Appl. Crystallogr. 28, 768–773 (1995).

    Article  CAS  Google Scholar 

  5. Owen, B.A.L., Lang, W.H. & McMurray, C.T. Nat. Struct. Mol. Biol. 16, 550–557 (2009).

    Article  CAS  Google Scholar 

  6. Lang, W.H. et al. Proc. Natl. Acad. Sci. USA 108, E837–E844 (2011).

    Article  CAS  Google Scholar 

  7. Gupta, S., Gellert, M. & Yang, W. Nat. Struct. Mol. Biol. 19, 72–78 (2012).

    Article  CAS  Google Scholar 

  8. Yamagata, A. & Tainer, J.A. EMBO J. 26, 878–890 (2007).

    Article  CAS  Google Scholar 

  9. Dunkle, J.A. et al. Science 332, 981–984 (2011).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the Department of Energy (DOE) program Integrated Diffraction Analysis Technologies, US National Institutes of Health (NIH) grant GM105404 and Berkeley Laboratory Directed Research and Development funds provided by the Director, Office of Science, DOE. Support for the MutSβ and DNA-repair studies came from NIH GM066359 (C.T.M.), NS060115 (C.T.M.) and CA092584 (C.T.M. and J.A.T.).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Cynthia T McMurray or John A Tainer.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Text and Figures

Supplementary Tables 1 and 2, Supplementary Note and Supplementary Methods (PDF 5315 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hura, G., Budworth, H., Dyer, K. et al. Comprehensive macromolecular conformations mapped by quantitative SAXS analyses. Nat Methods 10, 453–454 (2013). https://doi.org/10.1038/nmeth.2453

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.2453

  • Springer Nature America, Inc.

This article is cited by

Navigation