Skip to main content
Log in

Beyond the rainbow: new fluorescent proteins brighten the infrared scene

  • News & Views
  • Published:

From Nature Methods

View current issue Submit your manuscript

Two fluorescent proteins that emit in the far-red and infrared range for imaging applications in cells and in vivo are described.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Fluorescent proteins used for deep-tissue imaging in mammals.

References

  1. Subach, O.M. et al. Nat. Methods 8, 771–777 (2011).

    Article  CAS  Google Scholar 

  2. Filonov, G.S. et al. Nat. Biotechnol. 29, 757–761 (2011).

    Article  CAS  Google Scholar 

  3. Chalfie, M., Tu, Y., Euskirchen, G., Ward, W.W. & Prasher, D.C. Science 263, 802–805 (1994).

    Article  CAS  Google Scholar 

  4. Prasher, D.C., Eckenrode, V.K., Ward, W.W., Prendergast, F.G. & Cormier, M.J. Gene 111, 229–233 (1992).

    Article  CAS  Google Scholar 

  5. Deliolanis, N.C. et al. J. Biomed. Opt. 13, 044008 (2008).

    Article  Google Scholar 

  6. Shu, X., Shaner, N.C., Yarbrough, C.A., Tsien, R.Y. & Remington, S.J. Biochemistry 45, 9639–9647 (2006).

    Article  CAS  Google Scholar 

  7. Kedrin, D. et al. Nat. Methods 5, 1019–1021 (2008).

    Article  CAS  Google Scholar 

  8. Lin, M.Z. et al. Chem. Biol. 16, 1169–1179 (2009).

    Article  CAS  Google Scholar 

  9. Morozova, K.S. et al. Biophys. J. 99, L13–L15 (2010).

    Article  CAS  Google Scholar 

  10. Shcherbo, D. et al. Nat. Methods 7, 827–829 (2010).

    Article  CAS  Google Scholar 

  11. Fischer, A.J. & Lagarias, J.C. Proc. Natl. Acad. Sci. USA 101, 17334–17339 (2004).

    Article  CAS  Google Scholar 

  12. Shu, X. et al. Science 324, 804–807 (2009).

    Article  Google Scholar 

  13. Toh, K.C., Stojkovic, E.A., van Stokkum, I.H., Moffat, K. & Kennis, J.T. Phys. Chem. Chem. Phys. 13, 11985–11997 (2011).

    Article  CAS  Google Scholar 

  14. Sakaue-Sawano, A. et al. Cell 132, 487–498 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael Z Lin.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lin, M. Beyond the rainbow: new fluorescent proteins brighten the infrared scene. Nat Methods 8, 726–728 (2011). https://doi.org/10.1038/nmeth.1678

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.1678

  • Springer Nature America, Inc.

This article is cited by

Navigation