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Antimicrobials

Broad-spectrum antivirals

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Nanoparticle mimics of heparan sulfate proteoglycans offer a new strategy for the inhibition of a range of viral infections.

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Figure 1: Virus lifecycle and intracellular delivery of antiviral agents.
Figure 2: The mechanism of action of virucidal nanoparticles.

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Authors and Affiliations

  1. Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, 68198-5880, Nebraska, USA

    Benson J. Edagwa & Howard E. Gendelman

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  1. Benson J. Edagwa
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  2. Howard E. Gendelman
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Correspondence to Howard E. Gendelman.

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Edagwa, B., Gendelman, H. Broad-spectrum antivirals. Nat. Mater. 17, 114–116 (2018). https://doi.org/10.1038/nmat5064

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