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Wound healing

Enzymatically crosslinked scaffolds

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Microgel particle precursors bearing peptide substrates for human enzymes crosslink in wound sites to produce bioactive scaffolds in situ that rapidly recruit cells and promote dermal healing.

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Figure 1: Strategy for transforming peptide-derivatized microporous annealed particles (MAPs) into robust, cell-infiltrated scaffolds for wound healing.

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Authors and Affiliations

  1. David W. Grainger is in the Department of Pharmaceutics and Pharmaceutical Chemistry, and the Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112-5820, USA,

    David W. Grainger

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  1. David W. Grainger
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Correspondence to David W. Grainger.

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Grainger, D. Enzymatically crosslinked scaffolds. Nature Mater 14, 662–663 (2015). https://doi.org/10.1038/nmat4337

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