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Cardiovascular calcification

Orbicular origins

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The application of imaging techniques prevalent in materials science to the biological process of soft tissue calcification lends new insight into age-related cardiovascular disease.

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Figure 1: Trends and predictions of elderly and fibrocalcific aortic valve stenosis (FCAVS) patients in the US, and changes in paradigms explaining valve calcification and stenosis over time.
Figure 2: The potential role of spheroid nanoparticles in the pathogenesis of age-related cardiovascular calcification.

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Authors and Affiliations

  1. Jordan D. Miller is in the Division of Cardiovascular Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA,

    Jordan D. Miller

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  1. Jordan D. Miller
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Correspondence to Jordan D. Miller.

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Miller, J. Orbicular origins. Nature Mater 12, 476–478 (2013). https://doi.org/10.1038/nmat3663

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