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Plasmonic nanosensors

Inverse sensitivity

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Enzyme-modified plasmonic nanoparticles that generate a signal that is larger when the concentration of the target molecule is lower can detect ultralow levels of the cancer biomarker prostate-specific antigen in whole serum.

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Figure 1: The inverse-sensitivity mechanism of enzyme-modified plasmonic nanosensors2.

References

  1. Engvall, E. & Perlmann, P. Immunochemistry 8, 871–874 (1971).

    Article  CAS  Google Scholar 

  2. Rodríguez-Lorenzo, L., de la Rica, R., Álvarez-Puebla, R. A., Liz-Marzán, L. & Stevens, M. M. Nature Mater. 11, 604–607 (2012).

    Article  Google Scholar 

  3. Lal, S., Link, S. & Halas, N. J. Nature Photon. 1, 641–648 (2007).

    Article  CAS  Google Scholar 

  4. Anker, J. N. et al. Nature Mater. 7, 442–453 (2008).

    Article  CAS  Google Scholar 

  5. Chen, S., Svedendahl, M., Van Duyne, R. P. & Käll, M. Nano Lett. 11, 1826–1830 (2011).

    Article  CAS  Google Scholar 

  6. Nehl, C. L., Liao, H. W. & Hafner, J. H. Nano Lett. 6, 683–688 (2006).

    Article  CAS  Google Scholar 

  7. Giljohann, D. A. & Mirkin, C. A. Nature 462, 461–462 (2009).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Mikael Käll is at the Department of Applied Physics, Chalmers University of Technology, 412 96 Göteborg, Sweden,

    Mikael Käll

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  1. Mikael Käll
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Correspondence to Mikael Käll.

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Käll, M. Inverse sensitivity. Nature Mater 11, 570–571 (2012). https://doi.org/10.1038/nmat3365

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