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Biocatalysis

Unmasked by stretching

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The biocatalytic activity of enzyme-loaded responsive layer-by-layer films can be switched on and off by simple mechanical stretching. Soft materials could thus be used to trigger biochemical reactions under mechanical action, with potential therapeutic applications.

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Figure 1: Schematic of the mechanically sensitive biocatalytic material.

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Correspondence to Vladimir V. Tsukruk.

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Kharlampieva, E., Tsukruk, V. Unmasked by stretching. Nature Mater 8, 704–705 (2009). https://doi.org/10.1038/nmat2523

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