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Drug delivery

The heart of the matter

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A polymeric delivery vehicle, with neutral degradation products, keeps inflammation at bay during sustained drug release following myocardial infarction.

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Figure 1: Drug release from a degradable matrix.
Figure 2: The embedded drug and matrix degradation products are released as the matrix erodes.

References

  1. Sy, J. C. et al. Nature Mater. 7, 863–869 (2008).

    Article  CAS  Google Scholar 

  2. Luman, N. R., Smeds, K. A. & Grinstaff, M. W. Chem. Eur. J. 9, 5618–5626 (2003).

    Article  CAS  Google Scholar 

  3. Richards Grayson, A. C. et al. Nature Mater. 2, 767–772 (2003).

    Article  Google Scholar 

  4. Tabata, Y., Gutta, S. & Langer, R. Pharm. Res. 10, 487–496 (1993).

    Article  CAS  Google Scholar 

  5. Wang, C. et al. Nature Mater. 3, 190–196 (2004).

    Article  CAS  Google Scholar 

  6. Zelikin, A. N., Zawaneh, P. N. & Putnam, D. Biomacromolecules 7, 3239–3244 (2006).

    Article  CAS  Google Scholar 

  7. Zawaneh, P. N., Doody, A. M., Zelikin, A. N. & Putnam, D. Biomacromolecules 7, 3245–3251 (2006).

    Article  CAS  Google Scholar 

  8. Heffernan, M. J. & Murthy, N. Bioconjug. Chem. 16, 1340–1342 (2005).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. David Putnam is in the Department of Biomedical Engineering and the School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, New York 14853, USA. dap43@cornell.edu,

    David Putnam

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  1. David Putnam
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Putnam, D. The heart of the matter. Nature Mater 7, 836–837 (2008). https://doi.org/10.1038/nmat2309

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