The use of quantum dots as DNA nanosensors promises to significantly enhance the sensitivity of fluorescence-based DNA detection for medical diagnosis and biomolecular investigations.
This is a preview of subscription content, log in via an institution to check access.
References
Zhang, C. -Y., Yeh, H. -C., Kuroki, M. T. & Wang, T. -H. Nature Mater. 4, 826–831 (2005).
Selvin, P. R. Nature Struct. Biol. 7, 730–734 (2000).
Medintz, I. L. et al. Nature Mater. 2, 630–638 (2003).
Doose, S., Tsay, J. M., Pinaud, F. & Weiss, S. Anal. Chem. 77, 2235–2242 (2005).
McKendry, R. et al. Proc. Natl Acad. Sci. USA 99, 9783–9788 (2002).
Park, S. J., Taton, T. A. & Mirkin, C. A. Science 295, 1503–1506 (2002).
Tyagi, S. & Kramer, F. R. Nature Biotechnol. 14, 303–308 (1996).
Bonnet, G., Tyagi, S., Libchaber, A. & Kramer, F. R. Proc. Natl Acad. Sci. USA 96, 6171–6176 (1999).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Dubertret, B. DNA detectives. Nature Mater 4, 797–798 (2005). https://doi.org/10.1038/nmat1520
Issue Date:
DOI: https://doi.org/10.1038/nmat1520
- Springer Nature Limited
This article is cited by
-
Environmental applications and potential health implications of quantum dots
Journal of Nanoparticle Research (2012)
-
Highly sensitive rare cell detection based on quantum dot probe fluorescence analysis
Analytical and Bioanalytical Chemistry (2010)
-
Gold Nanoparticle Based FRET for DNA Detection
Plasmonics (2007)
-
Label-free detection of proteins using SERS-based immuno-nanosensors
NanoBiotechnology (2006)